Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep1090 | Thyroid cancer | ECE2016

Differential expression of mRNA of the vitamin D receptor, 1α-hydroxylase 25-hydroxy vitamin D and estrogen receptors in human explants and cell cultures of thyroid cancer and normal tissues

Somjen Dalia , Sharon Orli , Knoll Esther , Aizic Abraham , Fliss David , Limor Rona , Stern Naftali , Izkhakov Elena

Several studies indicated that estrogen receptors (ERs) and vitamin D receptor (VDR), as well 1α-hydroxylase 25-hydroxy vitamin D (1OHase) are expressed in various normal and cancerous cell types. To date, there are no reported studies on the different expressions of VDR, 1OHase and ERs, in human thyroid normal and cancer cells. This study addresses these questions. Tissues harvested from papillary thyroid cancer (PTC) and normal glands explants were used throughout eithe...